Programmed cell death ligand 1(CD274, or B7-H1, PD-L1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. CD274 is suggested a negative regulator of T and B cell, and play important role in mediating tolerance of lymphocytes to self-antigens.
純化方式
Affinity Purified
形式
Liquid
存儲(chǔ)緩沖液
Liquid in 0.01M PBS, pH 7.4, 0.2%(w/v) BSA, 0.09%(w/v) NaN3
保存溫度
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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